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Description

Identification of a six-gene signature associated with tumor mutation burden for predicting prognosis in patients with invasive breast carcinoma

PMC 2686390

Products of Lipoxygenase The metabolism of AA by the 5-, 12-, and 15-lipoxygenases (LOX) results in production of hydroperoxyeicosatetraenoic acids (HPETEs), which rapidly convert to hydroxy derivatives (HETEs)

In obesity-related inflammation, CSE deficiency in adipose tissue macrophages (ATMs) and perivascular adipose tissue (PVAT) drives systemic metabolic dysfunction, reversible by H 2 S application or CSE overexpression