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3.2 Metalloproteinase Tamoxifen successfully up-regulated expression of metalloproteinases-1, TIMP-1, and down-regulated expression of matrix metalloproteinase 9, MMP-9

It was reported that podocyte-specific loss of PHB2, a mitochondrial inner membrane structural protein led to early onset of proteinuria in 3-weeks and death after 5 weeks 45