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Structure of PINK1 and mechanisms of Parkinsons disease-associated mutations

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Neuroinflammation and the immune system Microglia mediate the immunomodulatory processes in the brain and play a crucial role in the neuroinflammation in PD, leading to chronic activation and releasing of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-1 beta (IL-1), which further increase the damage in neurons and promote disease progression 41

Its a humectant meaning that it can help the skin to attract water and then hold onto it

Bibcode:2006MMBR...70..830C