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Specifically, 2-O-methylation stabilizes helical regions [139, 140] and shifts the sugar pucker equilibrium toward the 3-endo conformation, which increases the overall rigidity of RNA duplexes [141, 142]

With a focus on dyslipidemia and coronary heart disease, topics will cover advanced lipid testing, myocardial infarction, congestive heart failure, the role of depression and stress in CHD, newly discovered risk factors, neuro-cardiology, the role of nutrition & supplementsin addition to integrative therapiesin the treatment of metabolic cardiology, and more

doi: 10.1016/j.ygyno.2021.09.025 66 PnkovTMitrovKHalamovTMrzlkovKPchaJChrudinovMet al

Biological Chemistry 301, 108062

Although rare, serious side effects have been noted, with gallbladder disease and pancreatitis among the most concerning