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Etanercept given every week subcutaneously Adalimumab given every 2 weeks subcutaneously Infliximab given every 6 to 8 weeks intravenously Certolizumab pegol given every 2 to 4 weeks subcutaneously Golimumab given monthly subcutaneously Simponi ARIA given every 8 weeks intravenously There are other, less common biologic agents that can interrupt the inflammatory process, including: Tocilizumab (Actemra) Sarilumab (Kevzara) Abatacept (Orencia) These too, are given either subcutaneously or through IV every few weeks

The Pre-monitory Phase: Surprisingly, this can start up to 72 hours before the onset of headache

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They are vital for treating conditions like pernicious anemia and neurological symptoms caused by B12 deficiency

If not treated, it can cause serious problems like neurological damage and anemia