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Other routes of administration such as taking vitamins orally are limited by many factors including time to absorption, suboptimal absorption rates due to digestive dysfunction, detoxification processed limiting dose available to the rest of the body, and often poor bioavailability of active ingredients found in common supplement brands

.,Martn-CmaraO,ArribasM,WellsG,Morales-TenorioM,Martn-RequeroA,PorrasGMenndezJCMultitarget hybrid fasudil derivatives as a new approach to the potential treatment of amyotrophic lateral sclerosis.2022;65(3):18671882 100

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