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Dihexa induces spinogenesis in cultured hippocampal neurons Actin-enriched spines increased in number in response to both dihexa (Figure 38B&D) and Nle'-AnglV (Figure 38C&D) following 5 days of treatment at 10 "12 M concentration that started on the 7 th day in vitro (DIV7) the results revealed a near 3-fold increase in the number of spines stimulated by dihexa and greater than 2-fold increase for Nle f -AngIV

10.1093/humupd/dmv021 [DOI] [PubMed] [Google Scholar] Gamulin O., Serec K., Bili V., Balarin M., Kosovi M., Drmi D., et al

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Namely, as curing of the wounds includes resolution of vessel constriction, the primary platelet plug, the secondary plug, and resolution of the clot (Stupnisek et al., 2012