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SLC6A14 is overexpressed in colorectal cancer (Lu et al., 2022), ER + breast cancer (Karunakaran et al., 2011), gastric cancer (Wang and Wang, 2022), pancreatic cancer (Schniers et al., 2022), and cervical cancer (Sikder et al., 2018), closely related to lower overall survival

Methods: Gene expression was analyzed using RNA sequencing (RNA-seq), single-cell RNA sequencing (scRNA-seq), and 10x spatial transcriptomics in primary human hepatic stellate cells (hHSCs) and a CCl4-liver fibrosis induced murine model

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Clemens, D

BPC 157 application largely counteracted changes at the microscopic level, including the formation of vacuoles and the loss of axons in the white matter, the formation of edema and the loss of motoneurons in the gray matter, and a decreased number of large myelinated axons in the rat caudal nerve from day 7