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57 Importantly, such patients may develop PAH without evidence of significant ILD

Statistics and reproducibility Statistical analyses were performed and plotted using GraphPad Prism 10.5.0 software

This difference may be explained by the results of in vitro binding studies, which showed that daratumumab can directly bind CD38 on RBCs, whereas isatuximab requires a cofactor (e.g., a mouse anti-CD38 antibody or a CD38 inhibitor), suggesting masking of the isatuximab epitope on RBCs in some patients [49, 50]

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This test kit can detect up to 14 G6PD gene mutations in one run and the results can be directly visualized as a precipitated dot on the membrane template to provide a readout of the patients G6PD allele