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Cagrilintide, a long-acting human amylin analogue, exerts both central and peripheral effects by enhancing satiety, delaying gastric emptying, and modulating postprandial glucagon secretion, whereas semaglutide acts on GLP-1 receptors in the central nervous system and peripheral tissues to regulate appetite, glycemic control, and energy balance

CLM and TMA edited the manuscript, and read and approved the final version of the manuscript and agree with the order of presentation of the authors

Among CagriSema-treated participants, 73.5% achieved HbA1c of 6.5% or below compared to 15.9% with placebo, demonstrating remarkable dual efficacy for both weight and glycemic endpoints

BPC-157 benefits are often discussed in the context of tendon healing, gut support, and recovery

Most research on BPC-157 has been conducted in animal models with promising results related to tissue repair and inflammation balance