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Common signs of a B12 deficiency include: Fatigue Weakness Pale skin Poor coordination Heart palpitations Loss of appetite Unexplained weight loss A B12 deficiency can also contribute to mental health issues like depression and cognitive issues like confusion and poor memory

Autoimmunity in Graves' ophthalmopathy: the result of an unfortunate marriage between TSH receptors and IGF-1 receptors

DOI: 10.1038/ejcn.2015.78, Kipp, A., Strohm, D., Brigelius-Flohe, R., et al

Its effects are indirect, but wide-rangingfrom fat loss to improved sleep and tissue repair

Since these hormones also decrease with age, boosting growth hormone without balancing sex hormones may have little effect