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Metabolic dysfunction-associated steatotic liver disease (MASLD) is the prevailing chronic hepatic disorder in Western societies, where it is characterized by hepatic steatosis affecting more than 5% of hepatocytes in the absence of excessive alcohol consumption ( 30 g/day for men and 20 g/day for women), or other underlying chronic liver diseases, and it is commonly associated with metabolic risk factors such as obesity and type 2 diabetes [4]

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Assays for DHT, using 14C-testosterone/14C-4-androstenedione as substrates in gingival and oral periosteal fibroblast cell cultures in response to nicotine and glutathione would be a suitable index of redox status in a simulated model of selected parameters

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Antibiotic-induced intestinal microbiota depletion can attenuate the acute kidney injury to chronic kidney disease transition via NADPH oxidase 2 and trimethylamine-N-oxide inhibition