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In this context, NQO1-mediated suppression of TBK1 signaling may represent a protective feedback mechanism to restrain excessive inflammation

Zhang Z, Wang J, Zhang R, Huang R (2012) The ethylene response factor AtERF98 enhances tolerance to salt through the transcriptional activation of ascorbic acid synthesis in Arabidopsis

Although the heritability of AD is high, knowledge of the disease-associated genes and their expression regulation still remains limited

The current study further explores the hypothesis that the application of metabolite-based biomarker techniques using decision thresholds derived from quantitative measurements can identify metabolic subpopulations of autistic individuals (6, 9, 10)

210 In addition, oligonucleotide-based gene therapy using miR mimic or agomiR, noncoding RNA inhibitors (antisense oligonucleotides, locked nucleic acid, antagomiR), small interfering RNA, and modified RNA, has also been applied to regulate gene expressions in vivo