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Along these lines, it has been reported that patients with IBD display an activated mucosal immune system, with high infiltration of plasma cells, neutrophils and macrophages, accompanied by overexpression of pro-inflammatory cytokines and various chemokines that promote the recruitment of inflammatory cells (64)

Nature 504 , 446450 (2013)

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Nat Commun 11:433

So people with autoimmune conditions, which, unfortunately, is a growing number of Americans and people around the world, are really in desperate need of natural and safe interventions that can move the needle