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An increase in eukaryotic translation initiation factor 3 subunit F (EIF3F) and Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 (MALT1) was also demonstrated to be reduced by BBR treatment of murine mast cells (100 M), suggesting that through inhibition of eotaxin and pro-inflammatory cytokines and the inflammatory cells recruited, BBR is able to improve AD symptoms, and this may be due to the downregulation of EIF3F and MALT1 [58]

However, the first experiment from the Middle East indicated its importance in disease development in humans

Lancet Neurol 15(13):13681376 Holguin JCM (2021) Mitochondrial Dysfunction and Refractory Epilepsy 3(1):1112 Hong Y, Wei C, Fu M, Li X, Zhang H, Yao B (2024) MCC950 alleviates seizure severity and angiogenesis by inhibiting NLRP3/ IL-1 signaling pathway-mediated pyroptosis in mouse model of epilepsy

So, is it a real thing

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