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Regulating ROS production and elimination in the body to achieve homeostasis is a potential mechanism for achieving anti-inflammatory effects

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Glob J Med Sci

On the other hand, the accumulation of AGEs can bind to RAGE in kidney cells, which further leads to the intracellular inflammation and oxidative stress signaling pathways, such as nuclear factor-B (NF-B), phosphatidylinositide 3-kinase/protein kinase B (PI3K/Akt) and mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK), etc