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A dose related reduction in body weights of fourth and fifth litter offspring of the treated mating pair occurred during lactation and post-weaning at all doses

Cell Reports Medicine , 6 (3), 101977 Alvarez, S

However, the scientific rationale suggests that their different mechanisms could complement each other

Results: In the WD/TN mouse model, TLC-065 was well-tolerated over 14 weeks of dosing and led to pronounced NASH regression, evidenced by normalization of hepatic inflammation and fibrosis to levels observed in chow mice without affecting hepatic steatosis (Fig A)