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in Cell Metabolism , increased NAD availability stimulates PGC-1 through SIRT1 activation, leading to enhanced mitochondrial function and improved metabolic flexibility (Cant et al., Cell Metabolism )

It may also appear in form of breathing trouble, dizziness, or swelling

Experts are studying it's natural anti-depressant effects and use in treatment of bi-polar disorder, OCD, bulimia, ADHD, Autism, schizophrenia, and Alzheimers disease