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For example, we found that liver-specific Slc39a14 knockout mice (Slc39a14 Alb/Alb ) do not accumulate Mn when fed a diet containing normal concentrations of Mn (10 ppm), suggesting that the loss of Slc39a14 in the liver does not induce spontaneous systemic Mn overload and progressive neuromotor deficits, which are typical phenotypes of global Slc39a14 knockout mice

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87 Older patients are more at risk for QT prolongation but are also more likely to have structural heart disease, drug interactions, and decreased drug clearance

He C, Zhang W, Gao Q, Yang A, Hu X, Zhang J (2011) Enhancement of drought resistance and biomass by increasing the amount of glycine betaine in wheat seedlings