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Researchers have noted dose-dependent variability in observed effects across different animal models, underscoring that findings from one species or injury model may not generalize to others

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[] DNA methylation DNA methylation typically leads to transcriptional repression by promoting a condensed chromatin structure through covalent attachment of a methyl group to the 5 carbon of cytosine bases, predominantly within cytosine-phosphate-guanine dinucleotide site (CpG) dinucleotides

placebo, n=10) were assessed as related to patients underlying disease or other causes

HIBI: Hypoxic-ischemic brain injury