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This step might involve acid-base catalysis by the active-site cysteinyl thiolate (which could explain an effect of the second cysteinyl residue), and/or the conserved lysine residue, yielding GS in analogy to glutathione transferases (Fig

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Journal: Org Biomol Chem (2014): 362 Glutathione peroxidase-1 is required for self-renewal of murine embryonic stem cells Authors: Wang QY, Liu ZS, Wang J, Wang HX, Li A, Yang Y, Wang XZ, Zhao YQ, Han QY, Cai H, Liang B, Song N, Li WH, Li T

In the conventional framework, immunoadjuvants are defined as molecules or compounds possessing intrinsic immunomodulatory properties that, when coadministered with an antigen, significantly amplify antigen-specific immune responses compared to antigen administration alone