mildly melanotic mucosa Malignant melanoma—cutaneous and mucosal. a, b Melanoma of the right Frontiers | Mucosal Melanoma: Pathological

Frontiers Mucosal Melanoma: Pathological Evolution, Pathway Dependency and Targeted Therapy Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Pigmented Lesions of the Oral Mucosa Springer Nature Link Pigmented Lesions of the Oral Mucosa: Clinical Presentation, Histology, and Recommendations for Management American Journal of Clinical Dermatology Springer Nature Link Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in

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