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Final results of phase II trial evaluating chemotherapy, concurrent chemoradiation and surgery in locoregionally advanced esophageal cancer

Abstract Nicotinamide adenine dinucleotide (NAD) and glutathione are vital molecules that control redox-state, enzyme functions and metabolic flux in hundreds of cellular metabolic reactions

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-Carotene treatment increases CAT activity (0.8945 0.018), showing its role in improving antioxidant defenses

Does the failure of any of these metabolic branches and nodes contribute to the induction of ferroptosis in organ damage and degenerative diseases beyond their roles in cancer