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Brand: nordic-walking-brno.cz
SKU: 38340410135
Price: 21.24 USD
Availability: InStock
Rating: 4.4545 (29 reviews)

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SKU: 38340410135 · From nordic-walking-brno.cz

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Description

Understanding the GTPase activity of LRRK2: regulation, function and neurotoxicity

Considering the emerging link between impaired cerebellar function and mania, and that decreased serum BDNF is a biomarker of bipolar disorder, the decrease in cerebellar BDNF expression in the Camkk2 and Camk4 null mice suggests that defects in CaMKK2-CaMK4 signalling within the cerebellum may be involved in triggering manic behaviour [46,47,48,49]